Fig. 2
From: Bapx1 upregulation is associated with ectopic mandibular cartilage development in amphibians
Effects of Ly-294,002 treatment on external head morphology and bapx1 expression in X. laevis. Lateral view of larvae at NF 44 after rearing in a 0,1× MBS as control, b 0,1 μM DMSO and c 20 μM Ly-294,002 from NF 29 onwards. No significant differences in the external morphology can be observed. In situ hybridisation of NF 37 X. laevis larvae raised in d 0,1xMBS as control and e 20 μM Ly-294,002 from NF 29 onwards in lateral view reveal differences in the expression of bapx1 in the mandibular arch. After bapx1 upregulation the mandibular arch expression domain is broader and extends postero-dorsally. Scale bar 500 μm